Avanafil 100 Mg side Effects

What is Avanafil 100 Mg ?

STENDRA (avanafil) is a selective inhibitor of cGMP-specific PDE5.

Avanafil is designated chemically as (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide and has the following structural formula:

Drug DescriptionD)

STENDRA (avanafil) is a selective inhibitor of cGMP-specific PDE5.
Avanafil is designated chemically as (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide and has the following structural formula:


Avanafil occurs as white crystalline powder, molecular formula C23H26ClN7O3 and molecular weight of 483.95 and is slightly soluble in ethanol, practically insoluble in water, soluble in 0.1 mol/L hydrochloric acid. STENDRA, for oral administration, is supplied as oval, pale yellow tablets containing 50 mg, 100 mg, or 200 mg avanafil debossed with dosage strengths. In addition to the active ingredient, avanafil, each tablet contains the following inactive ingredients: mannitol, fumaric acid, hydroxypropylcellulose, low substituted hydroxypropylcellulose, calcium carbonate, magnesium stearate, and ferric oxide yellow.

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Some of the side effects of Avanafil are as follows

Headache (5.6%)

Flushing (3.5%)

Nasal congestion (2.1%)

Nasopharyngitis (3.4%)

Back pain (2.5%)

Upper respiratory infection (<2%)

Bronchitis (<2%)

Influenza (<2%)

Sinusitis (<2%)

Sinus congestion (<2%)

Hypertension (<2%)

Dyspepsia (<2%)

Nausea (<2%)

Constipation (<2%)

Rash (<2%)

<1%

Peripheral edema

Fatigue

Angina

Deep vein thrombosis

Palpitations

Gastritis

Gastroesophageal reflux disease

Hypoglycemia

Hyperglycemia

Oropharyngeal pain

Stomach discomfort

Vomiting

Depression

Insomnia

Cough

Dyspnea exertional

Epistaxis

Wheezing

Pruritus

Urinary tract infection

Pollakiuria

Nephrolithiasis

Hematuria

Increased erection

Balanitis