All truth about Viagra
Sildenafil, which appeared on the market in the late 90s, is the first really effective drug that has helped solve the problem of erectile dysfunction to large number of men. According to statistics, about 150 million men from 18 years and older suffer from problems in sexual life and urination due to the disorder of blood circulation in the pelvic. One of the most popular and effective drugs for symptomatic treatment is Viagra. Today there are not less popular counterparts, and namely, German Levitra, American Cialis and other, but nevertheless, sildenafil keeps its position. Thanks to a big advertising campaign and truly innovative features, the drug is known all over the world.
Pharmacological action of Viagra
What is the process of erection? It is basis is hemodynamics or blood flow through the vessels in an area of low pressure. Smooth muscle of the cavernous body should be relaxed, nitric oxide is released in the body at the sexual arouse, more and more blood rushes to the penis, it swells and this is a natural reaction to the stimulation. But if the walls of the vessels resist the movement, the blood becomes more viscous, the difficulties arise and the process stops. The matter is that while the release of nitric oxide an enzyme that breaks down cGMP, a nucleotide in the RNA composition also begins to "work". And nitric oxide has no time to release in a sufficient amount; the enzyme continues to interfere with the rush of the blood. Viagra stops it. Thus during the arousal no physiological process does not prevent to occur the natural and normal erection.
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