Wednesday, March 6, 2019

Is Aspadol 100 MG Effective?

The 100 mg dose may be more effective for patients with some opioid tolerance or for severe pain. The IR form can be used as 50–100 mg every 4–6 hours as needed for pain, and on the first day of treatment up to 700 mg/day

LIMITATIONS:

Strict patient monitoring is generally not representative of real-world medical practice; consequently, higher incidences of TEAEs may have been reported than would be expected in a typical practice setting; it is anticipated that this bias would be similar for both treatment groups.

CONCLUSIONS:

This head-to-head study demonstrated that tapentadol IR had comparable analgesic efficacy and overall safety to that of oxycodone IR for the relief of moderate to severe, acute LBP and associated radicular leg pain when using flexible dosing regimens that reflect typical use in clinical practice; however, tapentadol IR demonstrated a better gastrointestinal tolerability profile, particularly for the common opioid-related TEAEs of vomiting and constipation.

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