What is Vardenafil used for?

LEVITRA (vardenafil hydrochloride) is administered orally for the treatment of erectile dysfunction. This monohydrochloride salt of vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

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Vardenafil HCl is a nearly colorless, solid substance with a molecular weight of 579.1 g/mol and a solubility of 0.11 mg/mL in water.
LEVITRA is formulated as orange, round, film-coated tablets with “BAYER” cross debossed on one side and “2.5”, “5”, “10”, and “20” on the other side corresponding to 2.5 mg, 5 mg, 10 mg, and 20 mg of vardenafil, respectively. In addition to the active ingredient, vardenafil HCl, each tablet contains microcrystalline cellulose, crospovidone, colloidal silicon dioxide, magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, yellow ferric oxide, and red ferric oxide.

Levitra is a prescription medication that helps men with erectile dysfunction to get and keep an erection. ... You can't buy Levitra tablets without a prescription but you can use our online consultation to obtain a prescription and erectile dysfunction treatment.

How does it work?

Vardenafil can help a man get and maintain an erection.

During a penile erection, the penis fills with blood.

The blood vessels that supply the penis with blood expand, or dilate, and the vessels that take blood away from the penis contract. The two large chambers in the penis, known as the corpus cavernosa, fill with blood.

As the blood accumulates in the penis, an erection results.

Vardenafil belongs to a class of drugs called phosphodiesterase type-5 (PDE5) inhibitors. A PDE5 inhibitor stops PDE5 from constricting the arteries.

By relaxing the arteries, vardenafil enhances blood flow when a man is sexually aroused.

The active ingredient works on the chain of reactions within the penis during arousal.

When a male is sexually aroused, nitric oxide is released into his penis, and this triggers a chain of reactions.

This causes an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP).

cGMP regulates the contraction and dilation, or expansion, of blood vessels that carry blood to and from the penis. The chemical reaction causes the vessels that supply the penis to dilate, while those removing blood from the penis contract.

Phosphodiesterase-5 (PDE5), another enzyme breaks down or destroys cGMP.

When cGMP is destroyed, the blood vessels return to their normal size, effectively ending the erection. Vardenafil stops PDE5 from destroying cGMP. In this way, it allows cGMP to work for longer. As a result, it helps prolong an erection.